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USA TODAY Sports photo of Patrick Mahomes

USA TODAY Sports photo of Patrick Mahomes

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Reigning league MVP Patrick Mahomes was ruled out of Thursday night's game in Denver by the Kansas City Chiefs in the second quarter with what's believed to be a significant right knee injury.

Mahomes, the Chiefs superstar coming off one of the best quarterbacking seasons in NFL history, has been playing through a high ankle sprain the past three weeks and suffered the injury on a fourth-and-1 QB sneak

Former longtime NFL team doctor David Chao posted a short while ago that based on video evidence, although the injury appears significant and most likely will require surgery, it's possible Mahomes can put it off until after the season and return in a few weeks.

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Mahomes, who'd completed 10 of his first 11 passes including a 21-yard touchdown to rookie Mecole Hardman, was replaced by veteran Matt Moore late in the second quarter with a 10-6 lead. The Chiefs then tacked on a 20-yard field goal and a five-yard Reggie Ragland fumble return touchdown and lead by 10 at halftime.

The 4-2 Chiefs are attempting to snap a two-game losing skid but now have much bigger concerns than tonight's outcome.

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This article originally ran on profootballweekly.com.

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